:root[data-site-style=material] .fullscreen-clock-stage .clock-stage-toolbar{grid-template-rows:auto;grid-template-columns:minmax(0,1fr) auto minmax(0,1fr);align-items:center;min-width:0}:root[data-site-style=material] .fullscreen-clock-stage{container:fullscreen-clock-stage/inline-size}:root[data-site-style=material] .fullscreen-clock-stage .clock-stage-view-switch{grid-area:1/2;justify-self:center;min-width:0}:root[data-site-style=material] .fullscreen-clock-stage .clock-stage-view-switch button{white-space:nowrap}:root[data-site-style=material] .fullscreen-clock-stage .clock-stage-actions{grid-area:1/3;justify-self:end;gap:5px;min-width:0}:root[data-site-style=material] .fullscreen-clock-stage:fullscreen{box-shadow:none;outline:0;margin:0}@media (width<=600px){:root[data-site-style=material] .fullscreen-clock-stage .clock-stage-toolbar{grid-template-rows:auto;grid-template-columns:minmax(0,1fr) auto;column-gap:8px;padding-inline:12px}:root[data-site-style=material] .fullscreen-clock-stage .clock-stage-view-switch{grid-area:1/1;justify-self:start}:root[data-site-style=material] .fullscreen-clock-stage .clock-stage-actions{grid-area:1/2;justify-self:end;gap:4px}:root[data-site-style=material] .fullscreen-clock-stage .clock-stage-view-switch button,:root[data-site-style=material] .fullscreen-clock-stage .clock-stage-actions button{flex:0 0 44px;width:44px;min-width:44px;min-height:44px}:root[data-site-style=material] .fullscreen-clock-stage .clock-stage-view-switch button{flex-basis:68px;gap:5px;width:68px;min-width:68px;padding-inline:7px;font-size:13px}:root[data-site-style=material] .fullscreen-clock-stage .clock-stage-view-switch button svg{flex:0 0 18px;width:18px;height:18px}}@media (width<=360px){:root[data-site-style=material] .fullscreen-clock-stage .clock-stage-toolbar{grid-template-rows:auto auto;grid-template-columns:minmax(0,1fr);gap:7px 4px}:root[data-site-style=material] .fullscreen-clock-stage .clock-stage-view-switch{grid-area:1/1;justify-self:center}:root[data-site-style=material] .fullscreen-clock-stage .clock-stage-actions{grid-area:2/1;justify-self:end;gap:2px}:root[data-site-style=material] .fullscreen-clock-stage .clock-stage-actions button,:root[data-site-style=material] .fullscreen-clock-stage .clock-stage-view-switch button{flex:0 0 44px;gap:4px;width:44px;min-width:44px;min-height:44px;padding-inline:3px}:root[data-site-style=material] .fullscreen-clock-stage .clock-stage-view-switch button{flex-basis:68px;width:68px;min-width:68px;padding-inline:7px}}@media (orientation:portrait) and (width>=601px) and (width<=900px){:root[data-site-style=material] .fullscreen-clock-stage .clock-stage-toolbar{grid-template-rows:auto;grid-template-columns:minmax(0,1fr) auto;column-gap:12px;padding-inline:16px}:root[data-site-style=material] .fullscreen-clock-stage .clock-stage-brand{display:none}:root[data-site-style=material] .fullscreen-clock-stage .clock-stage-view-switch{grid-column:1;justify-self:start}:root[data-site-style=material] .fullscreen-clock-stage .clock-stage-actions{grid-column:2;justify-self:end}}@container fullscreen-clock-stage (width<=520px){:root[data-site-style=material] .fullscreen-clock-stage .clock-stage-toolbar{grid-template-rows:auto auto;grid-template-columns:minmax(0,1fr) auto;row-gap:7px}:root[data-site-style=material] .fullscreen-clock-stage .clock-stage-brand{display:none}:root[data-site-style=material] .fullscreen-clock-stage .clock-stage-view-switch{grid-area:1/1;justify-self:center}:root[data-site-style=material] .fullscreen-clock-stage .clock-stage-actions{grid-area:2/1/auto/-1;justify-self:center}:root[data-site-style=material] .fullscreen-clock-stage .clock-stage-actions .view-mode-button{position:absolute;top:12px;right:12px}}.bioinformatics-workbench{container-type:inline-size}.bio-field{min-width:0;color:var(--text-secondary);gap:7px;font-size:12px;display:grid}.bio-field>span{color:var(--text-tertiary);justify-content:space-between;align-items:baseline;gap:10px;font-weight:700;display:flex}.bio-field>span small{color:var(--text-tertiary);font-size:10px;font-weight:500}.bio-field input,.bio-field select,.bio-field textarea{width:100%;min-width:0;color:var(--text-primary);background:var(--surface-muted);border:1px solid var(--border);font:inherit;border-radius:6px;outline:none}.bio-field input,.bio-field select{min-height:40px;padding:0 10px}.bio-field textarea{resize:vertical;min-height:250px;padding:12px;font-family:ui-monospace,SFMono-Regular,Consolas,monospace;line-height:1.6}.bio-field input:focus,.bio-field select:focus,.bio-field textarea:focus{border-color:var(--accent-border);box-shadow:0 0 0 3px var(--accent-soft)}.bio-sequence-field{margin:8px 0 14px}.bio-tool-hint{color:var(--text-tertiary);margin:4px 0 14px;font-size:12px;line-height:1.6}.bio-control-grid{grid-template-columns:repeat(3,minmax(0,1fr));gap:12px;margin:12px 0 16px;display:grid}.bio-actions{flex-wrap:wrap;align-items:center;gap:8px;margin:12px 0;display:flex}.bio-error{color:var(--danger);background:color-mix(in srgb, var(--danger) 8%, var(--surface-solid));border:1px solid color-mix(in srgb, var(--danger) 35%, var(--border));border-radius:6px;margin:12px 0;padding:10px 12px;font-size:12px}.bio-result{border-top:1px solid var(--border);margin-top:20px;padding-top:16px}.bio-result-heading{justify-content:space-between;align-items:center;gap:10px;margin-bottom:12px;display:flex}.bio-result-heading h3{color:var(--text-primary);margin:0;font-size:16px}.bio-result-heading .bio-actions{margin:0}.bio-result pre{max-height:260px;color:var(--text-secondary);background:var(--canvas);border:1px solid var(--border);white-space:pre-wrap;border-radius:6px;margin:14px 0 0;padding:12px;font-family:ui-monospace,SFMono-Regular,Consolas,monospace;font-size:12px;line-height:1.65;overflow:auto}.bio-stat-grid{grid-template-columns:repeat(4,minmax(0,1fr));gap:8px;display:grid}.bio-stat{background:var(--surface-muted);border:1px solid var(--border);border-radius:6px;gap:4px;min-width:0;padding:11px;display:grid}.bio-stat strong{min-width:0;color:var(--text-primary);overflow-wrap:anywhere;font-size:17px}.bio-stat span{color:var(--text-tertiary);font-size:10px}.bio-calc-tabs{background:var(--surface-muted);border:1px solid var(--border);border-radius:8px;flex-wrap:wrap;gap:4px;margin-bottom:14px;padding:4px;display:flex}.bio-calc-tabs button{min-height:34px;color:var(--text-secondary);cursor:pointer;font:inherit;background:0 0;border:0;border-radius:6px;padding:0 13px;font-size:12px;font-weight:700}.bio-calc-tabs button:hover,.bio-calc-tabs button.active{color:var(--md-on-primary-container,var(--text-primary));background:var(--accent-soft)}.bio-input-with-unit{grid-template-columns:minmax(0,1fr) 92px;gap:6px;display:grid}.bio-result-rows{border:1px solid var(--border);border-radius:6px;gap:0;display:grid;overflow:hidden}.bio-result-rows>div{background:var(--surface-muted);border-bottom:1px solid var(--border);justify-content:space-between;align-items:center;gap:12px;min-height:42px;padding:0 12px;font-size:12px;display:flex}.bio-result-rows>div:last-child{border-bottom:0}.bio-result-rows span{color:var(--text-secondary)}.bio-result-rows strong{color:var(--accent-deep);text-align:right}.bio-note,.bio-check-note{color:var(--text-tertiary);margin:11px 0 0;font-size:11px;line-height:1.6}.bio-primer-grid{grid-template-columns:repeat(2,minmax(0,1fr));gap:12px;display:grid}.bio-primer-card{background:var(--surface-muted);border:1px solid var(--border);border-radius:7px;min-width:0;padding:13px}.bio-primer-card h3{color:var(--text-primary);margin:0 0 10px;font-size:13px}.bio-mini-grid{grid-template-columns:repeat(2,minmax(0,1fr));gap:7px;display:grid}.bio-mini-grid span{color:var(--text-tertiary);gap:2px;font-size:10px;display:grid}.bio-mini-grid strong{color:var(--text-primary);font-size:14px}@container (width<=620px){.bio-control-grid,.bio-primer-grid{grid-template-columns:1fr}.bio-stat-grid{grid-template-columns:repeat(2,minmax(0,1fr))}.bio-result-heading{flex-direction:column;align-items:flex-start}}